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Microsoft Office 2010 (32 bit) is not officially supported in Exact Synergy. However, it is possible to use Microsoft Office 2010 (32 bit), and Exact does not provide any support on this besides this document.  In order to access, you need to disable the Enable Data Execution Prevention mode setting in Microsoft Outlook. The following steps will take you through the configuration.
Note: These steps are applicable only to 32 bit version of Microsoft Office 2010 and Microsoft Windows.  
  • Go to Microsoft Outlook.
  • Click File tab.  
  • Under Help, click Options. The Options dialog screen appears.
  • Click Trust Center, then click Trust Center Settings.
  • In the Trust Center, click DEP Settings.
  • Under DEP Settings, do not select the Enable Data Execution Prevention mode check box.

For more information, see Data Execution Prevention.